A 2026 systematic review and meta-analysis evaluating seven in vitro studies compared the cyclic fatigue resistance of EdgeTaper Platinum and ProTaper Gold rotary files. The analysis found that EdgeTaper Platinum consistently demonstrated superior cyclic fatigue resistance, with the pooled data showing a statistically significant advantage over ProTaper Gold. Increased cyclic fatigue resistance may help reduce the risk of instrument separation when treating curved canals, supporting greater confidence during root canal procedures. While the authors noted that additional standardized studies are warranted to further validate these findings under clinical conditions, the current body of evidence highlights EdgeTaper Platinum’s consistent mechanical performance across a range of laboratory testing models.